Methods of determining the amounts of chemical substances present in solutions, by the employment of reagents of definite strength in connection with wellunderstood interactions. To determine, for example, the amount of free iodine contained in an acidified solution of potassium iodide, a standardized solution of sodium hyposulphite is employedthat is to say, a solution of predetermined strengthand this is gradually run into the subject mixture, from a burette until the colour has entirely disappeared. It is then easy to calculate from the known chemical interaction that takes place the amount of free iodine in the mixture. The interaction is represented as follows: I2 + 2tsa2S203 = 2NaI + NaO,. that is to say, the free iodine is converted into potassium iod

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