- Ludwig Method. A method for the estimation of uric acid in solution. When an ammoniacal solution of nitrate of silver is added to a solution of uric acid, to which a mixture of magnesium chlorid and ammonium chlorid has been previously added, the uric acid is precipitated as a mag- nesio-silver salt. This is collected, washed, and decomposed by sodium or potassium sulphid, whereupon the uric acid passes again into solution as a urate of the alkali. On the addition of an excess of HCI to this solution the urate is decomposed, uric acid separates out and is collected and weighed.
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